| Pair Name | Saikosaponin B1, Etoposide | ||
| Phytochemical Name | Saikosaponin B1 (PubChem CID: 9875547 ) | ||
| Anticancer drug Name | Etoposide (PubChem CID: 36462 ) | ||
| Structure of Phytochemical |
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2D
MOL
3D
MOL
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| Structure of Anticancer Drug |
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| Pair Name | Saikosaponin B1, Etoposide | |||
| Disease Info | [ICD-11: 2C30] | Melanoma | Investigative | |
| Biological Phenomena | Induction-->DNA damage | |||
| Gene Regulation | Down-regulation | Activity | NFKB1 | hsa4790 |
| Up-regulation | Expression | H2AX | hsa3014 | |
| In Vitro Model | B16-F10 | Mouse melanoma | Mus musculus (Mouse) | CVCL_0159 |
| Result | We conclude Saikosaponin B can be an attractive adjuvant for enhancing the clinical effect of cancer chemotherapy. | |||
| No. | Title | Href |
|---|---|---|
| 1 | Chemosensitizing Effect of Saikosaponin B on B16F10 Melanoma Cells. Nutr Cancer. 2017 Apr;69(3):505-511. doi: 10.1080/01635581.2017.1285407. | Click |
